SANA quoted a military source as saying the bus was hit overnight on a desert road in the Dayr al-Zawr Province.
Meanwhile, the Lebanon-based Al-Mayadeen quoted a Syrian security source as saying that 20 soldiers were killed and ten more wounded in the attack.
Daesh members in recent weeks have increased their surprise attacks in Syria’s north and northeast, where they maintain hideouts.
The group, which seized wide swathes of Syria and neighboring Iraq from 2013, went underground since it lost its last territory in eastern Syria in 2019.